I used creatine 8 or so years ago, had great gains, ( it was the exact same product then & dont tell me its gotten better becasue its effervescent or some .) But I also had a frequent & uncomfortable need to urinate that was NOT just from consuming extra liquid, but from my kidneys being put on overload & doing damage to them with this stuff. I drank plenty of water, took a little less than the recommended dose & was having the urination problem for years after the use of creatine… I also was very short tempered with my family & young kids at the time I took it as it altered my mood.
I also have a friend who underwent a kidney transplant, that if he didnt get, he would have died . the reason for his kidney failure was creatine & he would tell you to stay far away from it as it almost costed him his life. This stuff is absolutely no good-
But not every side effect is a bad one. Some are downright welcome. Take finasteride . Introduced in 1992 to treat noncancerous enlargement of the prostate gland , it was found to regrow hair (and is marketed for that purpose under the name Propecia). Today, millions of men use a low dose of finasteride to treat male pattern baldness . Similarly, minoxidil , originally marketed as an oral tablet for high blood pressure , was found to grow hair in those using it. Today, as a topical lotion or foam, it is a popular over-the-counter remedy for baldness.
Scientists continue to work on better ways to design, conduct and evaluate non-randomized (., observational) studies to assess how well flu vaccines work. CDC has been working with researchers at universities and hospitals since the 2003-2004 flu season to estimate how well flu vaccine works through observational studies using laboratory-confirmed flu as the outcome. These studies currently use a very accurate and sensitive laboratory test known as RT-PCR (reverse transcription polymerase chain reaction) to confirm medically-attended flu virus infections as a specific outcome. CDC’s studies are conducted in five sites across the United States to gather more representative data. To assess how well the vaccine works across different age groups, CDC’s studies of flu vaccine effects have included all people aged 6 months and older recommended for an annual flu vaccination. Similar studies are being done in Australia, Canada and Europe. More recently, CDC has set up a second network the Hospitalized Adult Influenza Vaccine Effectiveness Network (HAIVEN) that looks at how well flu vaccine protects against flu-related hospitalization among adults aged 18 and older.