Lysyl oxidase has been newly implicated in tumor angiogenesis , or blood vessel formation, both in vivo and in vitro . Subcutaneous tumor-derived LOX was shown to increase vascular endothelial growth factor (VEGF) expression and secretion, which then promotes angiogenesis by phosphorylation of protein kinase B , or Akt, through platelet-derived growth factor receptor β ( PDGFRB ). High levels of LOX were associated with high blood vessel density in patient samples. Clinically relevant LOX inhibitors may help slow cancer progression by downregulating crucial growth factors that promote solid tumor progression. 
A quote from BFS, "[Out of all the people who take steroids, the fact is, x amount will suffer the harsh side effects]" It is a risk taken, knowingly, by those of us who choose to participate. Nobody is sticking anything in ourselves, but ourselves. I am sure if the % rate started to climb, the more people would rethink, but the fact remains is its that x % that suffer and the majority are fine. Now this doesn't mean that we should ignore this percentage, after all they are people, just like you and I and they share the same passion we all do and certainly we must not sit back and say "sorry bro, its gotta happen to someone." I really believe this "pushing the limit," in bodybuilding will eventually be its downfall. I was happy to see an earlier article on the return of "Classic Bodybuilding," guys weighing 200 and less, still big, still jacked, but not looking like the new hollywood Hulk. It was "is" about symmetry, proportion, muscularity. Not overall how big you are! A lot of changes need to taken and precautions to reverse this trend in BB that I believe can really help lower some of these tragic articles of our fellow brethren that we continue to get fed by the news. May bodybuilding and steroids live on! but only if we take a step back and look at what were really creating.
The Oral Steroids Winstrol & Anavar:The Oral Steroids Winstrol & Anavar:The Oral Steroids Winstrol & Anavar:vWhile both of these oral steroids can be used for both bulking and cutting, most male anabolic steroid users will be better served using them as a part of a leaning or cutting cycle. Neither drug will produce abundant gains in size but they serve as a well refined tool in terms of holding on to strength as well as helping produce a harder physique. As it pertains to Winstrol, some may find a more suitable use during an off-season period in conjunction with other anabolic steroids; an increase in strength is always a welcomed attribute but do not expect to see the scale move upward in serious fashion due to Winstrol use. The same cannot be said of Anavar; most men will find Anavar suited only for cutting cycles but be aware, there are far better suited anabolic steroids we can use for this purpose but don’t be fooled, Anavar does have a place in both bulking and cutting cycles. Anavar is not only one of the best oral steroids for females it is one of the best anabolic steroids for female’s period. Due to its very mild effects Anavar is one of the safest anabolics a woman can use and in general at a very low dose and still see fantastic results. Anavar can be successfully used by women during both bulking and cutting cycles quite well.