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A small number of studies have shown short term benefit from alcohol injections. However, the Centre has some concerns over the potential for injury and irritation to adjacent tissues as the alcohol cannot be isolated (unlike cryosurgery) to only target the neuroma. There is anecdotal evidence of increased pain from alcohol injections and there are documented complications (longer term nerve pain and sensitivity) which the Centre has not encountered from cryosurgery. Whilst the procedure has been offered in the UK it remains uncommon.