HL should be diagnosed by biopsy for definitive diagnosis. Experienced clinicians can make a presumptive diagnosis of HL in association with HIV disease from the clinical appearance, although HL can be confused with oral candidiasis. The typical microscopic appearance of HL includes acanthosis, marked parakeratosis with the formation of ridges and keratin projections, areas of ballooning cells, and little or no inflammation in the connective tissue. The ballooning changes resemble koilocytosis. Cells are enlarged; some contain enlarged ballooning cells with pyknotic nuclei. Some contain perinuclear haloes.
Vaginal yeast infections are typically treated with topical antifungal agents.  A one-time dose of fluconazole is 90% effective in treating a vaginal yeast infection.  For severe nonrecurring cases, several doses of fluconazole is recommended.  Local treatment may include vaginal suppositories or medicated douches . Other types of yeast infections require different dosing. Gentian violet can be used for thrush in breastfeeding babies. C. albicans can develop resistance to fluconazole, this being more of an issue in those with HIV/AIDS who are often treated with multiple courses of fluconazole for recurrent oral infections. 
Candidiasis: Disease caused by the yeast Candida albicans. Candida albicans can cause vaginal yeast infections, diaper rash , skin rashes that emerge in moist, warm folds of skin, and thrush (white patches inside the mouth and throat). Candidiasis tends to develop when the normal balance of bacteria is upset, as sometimes occurs with the use of antibiotics. Prevention measures include the use of probiotics , and in some cases, dietary changes. Candidiasis can be treated with antifungal medications. Candidiasis is usually a minor and easily addressed problem, but it can be an important problem for those with immune-system disorders, such as AIDS.