Maintenance therapy with either azathioprine or methotrexate is initiated if remission has occurred after three to six months of induction therapy. Steroid dosage is tapered during this phase. Patients may need to continue maintenance treatment for up to 24 months. 24 Maintenance treatment for up to five years is recommended in patients with Wegener granulomatosis and patients who remain ANCA-positive. 19 Some patients may require treatment indefinitely. Disease relapse may occur anytime after the remission. Serial measurements of ANCA are not closely associated with disease activity; therefore, treatment should not be solely guided on the basis of an increase in ANCA. 25 Relapsing disease can be managed with an increase in steroid dose, optimization of the current immunosuppressant, or combination of an immunosuppressant with an increased dose of steroid.
Q. Mood- disorder? What will happen to the people who refuse treatment? I know someone whose mother got diagnosed with "mood- disorder" and now this person says that she don't have it. But all her brothers and sisters have this, and are on medication. Is there a way to save our family heritage? A. well done, i will start to collect with the agreement of Iri possible causes for disorders (bipolar, mood, whatever you want to call it) to help people to recognize themselves. they all can start in the moment we are in the embryo. parental conflicts, aggressions, sexual behaviours, drugs, alcohol, smoking in abondance can affect us from this moment on.