Because men do not go through a well-defined period referred to as menopause, some doctors refer to this problem as androgen (testosterone) decline in the aging male, or what some people call low testosterone . Men do experience a decline in the production of the male hormone testosterone with aging , but this also occurs with conditions such as diabetes . Along with the decline in testosterone, some men experience symptoms that include fatigue , weakness , depression , and sexual problems. The relationship of these symptoms to decreased testosterone levels is still controversial.
Xerostomia, resulting from radiation injury of the salivary gland, is common with irradiation of the head and neck, especially with concurrent chemotherapy. Xerostomia is treated conservatively with saliva substitutes (., water or glycerin-based) and saliva stimulants (., sour sweets, chewing gum). Pilocarpine is more effective than artificial saliva, although its effectiveness may not be seen until 12 weeks of therapy. 23 Mucositis from radiation damage of the oral epithelium responds to topical anesthetics. Oral candidiasis is treated with topical anti-fungal washes or systemic antifungal agents. Amifostine (Ethyol), a free-radical scavenger radioprotectant, is beneficial in preventing and treating xerostomia, but there is insufficient evidence to support its use for radiation-induced mucositis and esophagitis. 24
Anabolic androgenic steroids (AAS) were initially created for therapeutic purposes, and synthetic derivatives of the male hormone testosterone. Due its great anabolic effects, these drugs are being used on a large scale, for the improvement of sports performance. In this present study, we aim to show the history of it’ use, present their mechanisms of action, more particularly its use correlate with improved body composition, muscle mass, aerobic capacity and verify their possible side effects, analyzing their use therapeutic and indiscriminate, through direct scientific research with the sports. Sources were reviewed scientific the following search engines: PUBMED, LILACS and SCIELO. The results showed that in presence of a suitable AAS and diet can contribute to increases in body weight, particularly lean body mass and muscle strength gains achieved by high intensity exercise, these effects can be further potentiated, the use of supraphysiological doses, but in the aspect of aerobic power, there are not scientific evidence to support their improvement. Regarding side effects, the use of AAS, is related to several complications in the liver, cardiovascular system, reproductive system and psychological characteristics, always assigned by the non-therapeutic and abuse of AAS. Thus we conclude that the use of AAS, are directly linked to gains muscle mass, strength, as well several side effects, always assigned to abusive and indiscriminate doses, it is noteworthy that the scientific literature, still has a certain lack of studies, mainly randomized, controlled, with supraphysiological doses in human, so many effects are still unknown.