Scientists have attempted to test the association between anabolic steroids and aggression by administering high steroid doses or placebo for days or weeks to human volunteers and then asking the people to report on their behavioral symptoms. To date, four such studies have been conducted. In three, high steroid doses did produce greater feelings of irritability and aggression than did placebo, although the effects appear to be highly variable across individuals. In one study, the drugs did not have that effect. One possible explanation, according to the researchers, is that some but not all anabolic steroids increase irritability and aggression. Recent animal studies show an increase in aggression after steroid administration.
You do not need large amounts of grapefruit juice or grapefruit to slow down your body’s ability to metabolize prohormones, and other medication and supplements. Even a glass of regular grapefruit juice could prevent your body from absorbing medications or supplements by almost 47 percent. Grapefruit juice’s effects on the CYP34A enzyme slowly wears off. Even 24 hours post ingestion, the juice could still prevent prohormone metabolism in excess of 15 percent. Therefore, get in touch with your doctor before administering prohormone supplements or merging grapefruit or its juice with any other supplement or medication.